CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.590.20
Functional Family Glutamate--cysteine ligase

Enzyme Information

6.3.2.2
Glutamate--cysteine ligase.
based on mapping to UniProt O23736
ATP + L-glutamate + L-cysteine = ADP + phosphate + gamma-L-glutamyl-L- cysteine.
-!- Can use L-aminohexanoate in place of glutamate.

UniProtKB Entries (1)

O23736
GSH1_BRAJU
Brassica juncea
Glutamate--cysteine ligase, chloroplastic

PDB Structure

PDB 2GWD
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for the redox control of plant glutamate cysteine ligase.
Hothorn, M., Wachter, A., Gromes, R., Stuwe, T., Rausch, T., Scheffzek, K.
J.Biol.Chem.