CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.170 | Beta Complex | |
2.170.8 | Phosphoenolpyruvate Carboxykinase; domain 2 | |
2.170.8.10 | Phosphoenolpyruvate Carboxykinase, domain 2 |
Domain Context
CATH Clusters
Superfamily | Phosphoenolpyruvate Carboxykinase, domain 2 |
Functional Family | phosphoenolpyruvate carboxykinase, cytosolic [GTP] |
Enzyme Information
4.1.1.32 |
Phosphoenolpyruvate carboxykinase (GTP).
based on mapping to UniProt P35558
GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO(2).
-!- ITP can act as phosphate donor.
|
UniProtKB Entries (1)
P35558 |
PCKGC_HUMAN
Homo sapiens
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
|
PDB Structure
PDB | 2GMV |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
C-8 Modifications of 3-alkyl-1,8-dibenzylxanthines as inhibitors of human cytosolic phosphoenolpyruvate carboxykinase.
Bioorg.Med.Chem.Lett.
|