CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.449 | Phosphoenolpyruvate Carboxykinase; domain 1 |
|
3.40.449.10 | Phosphoenolpyruvate Carboxykinase, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Phosphoenolpyruvate Carboxykinase, domain 1 |
| Functional Family | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] |
Enzyme Information
| 4.1.1.32 |
Phosphoenolpyruvate carboxykinase (GTP).
based on mapping to UniProt P35558
GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO(2).
-!- ITP can act as phosphate donor.
|
UniProtKB Entries (1)
| P35558 |
PCKGC_HUMAN
Homo sapiens
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
|
PDB Structure
| PDB | 2GMV |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
C-8 Modifications of 3-alkyl-1,8-dibenzylxanthines as inhibitors of human cytosolic phosphoenolpyruvate carboxykinase.
Bioorg.Med.Chem.Lett.
|