CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.379 | Chitobiase; domain 2 |
|
3.30.379.10 | Chitobiase/beta-hexosaminidase domain 2-like |
Domain Context
CATH Clusters
| Superfamily | Chitobiase/beta-hexosaminidase domain 2-like |
| Functional Family | Beta-hexosaminidase subunit beta |
Enzyme Information
| 3.2.1.52 |
Beta-N-acetylhexosaminidase.
based on mapping to UniProt P06865
Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.
-!- Acts on N-acetylglucosides and N-acetylgalactosides. -!- Formerly EC 3.2.1.29 and EC 3.2.1.30.
|
UniProtKB Entries (1)
| P06865 |
HEXA_HUMAN
Homo sapiens
Beta-hexosaminidase subunit alpha
|
PDB Structure
| PDB | 2GJX |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystallographic structure of human beta-Hexosaminidase A: Interpretation of Tay-Sachs Mutations and Loss
of GM2 Ganglioside Hydrolysis
J.Mol.Biol.
|
