CATH Domain 2gifA04

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.2090	Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
	3.30.2090.10	Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains

Domain Context

CATH Clusters

Superfamily	Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Functional Family	Efflux pump membrane transporter

Enzyme Information

UniProtKB Entries (1)

ACRB_ECOLI

Escherichia coli K-12

Multidrug efflux pump subunit AcrB

PDB Structure

PDB	2GIF
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism. Seeger, M.A., Schiefner, A., Eicher, T., Verrey, F., Diederichs, K., Pos, K.M. Science