CATH Domain 2ggpB00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.100

Domain Context

CATH Clusters

Superfamily	3.30.70.100
Functional Family	Copper-transporting ATPase 2

Enzyme Information

7.2.2.8

P-type Cu(+) transporter.

based on mapping to UniProt P38995

ATP + H(2)O + Cu(+)(Side 1) = ADP + phosphate + Cu(+)(Side 2).

-!- A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. -!- This enzyme transports Cu(+) or Ag(+), and cannot transport the divalent ions, contrary to EC 7.2.2.9, which mainly transports the divalent copper ion. -!- Formerly EC 3.6.3.54.

UniProtKB Entries (1)

P38995

ATU2_YEAST

Saccharomyces cerevisiae S288C

Copper-transporting ATPase

PDB Structure

PDB	2GGP
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism	Escherichia
Primary Citation	The Atx1-Ccc2 complex is a metal-mediated protein-protein interaction. Banci, L., Bertini, I., Cantini, F., Felli, I.C., Gonnelli, L., Hadjiliadis, N., Pierattelli, R., Rosato, A., Voulgaris, P. Nat.Chem.Biol.