CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.40 | Barwin-like endoglucanases |
|
2.40.40.10 | RlpA-like domain |
Domain Context
CATH Clusters
| Superfamily | RlpA-like domain |
| Functional Family | Membrane-bound lytic murein transglycosylase A |
Enzyme Information
| 4.2.2.n1 |
Peptidoglycan lytic exotransglycosylase.
based on mapping to UniProt P0A935
Exolytic cleavage of the (1->4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in peptidoglycan, from either the reducing or the non-reducing ends of the peptidoglycan chains, with concomitant formation of a 1,6-anhydrobond in the MurNAc residue.
|
UniProtKB Entries (1)
| P0A935 |
MLTA_ECOLI
Escherichia coli K-12
Membrane-bound lytic murein transglycosylase A
|
PDB Structure
| PDB | 2GAE |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal Structures of the Lytic Transglycosylase MltA from N.gonorrhoeae and E.coli: Insights into Interdomain Movements and Substrate Binding.
J.Mol.Biol.
|
