CATH Domain 2gabA00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.180	Transthyretin/hydroxyisourate hydrolase domain

Domain Context

CATH Clusters

Superfamily	Transthyretin/hydroxyisourate hydrolase domain
Functional Family	Transthyretin

Enzyme Information

UniProtKB Entries (1)

TTHY_HUMAN

Homo sapiens

Transthyretin

PDB Structure

PDB	2GAB
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Hydroxylated polychlorinated biphenyls selectively bind transthyretin in blood and inhibit amyloidogenesis: rationalizing rodent PCB toxicity Purkey, H.E., Palaninathan, S.K., Kent, K.C., Smith, C., Safe, S.H., Sacchettini, J.C., Kelly, J.W. Chem.Biol.