CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family tRNA (guanine-N(7)-)-methyltransferase

Enzyme Information

2.1.1.33
tRNA (guanine(46)-N(7))-methyltransferase.
based on mapping to UniProt O34522
S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.
-!- The enzyme specifically methylates guanine(46) at N(7) in tRNA.

UniProtKB Entries (1)

O34522
TRMB_BACSU
Bacillus subtilis subsp. subtilis str. 168
TRNA (guanine-N(7)-)-methyltransferase

PDB Structure

PDB 2FCA
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of Bacillus subtilis TrmB, the tRNA (m7G46) methyltransferase.
Zegers, I., Gigot, D., van Vliet, F., Tricot, C., Aymerich, S., Bujnicki, J.M., Kosinski, J., Droogmans, L.
Nucleic Acids Res.
CATH-Gene3D is a Global Biodata Core Resource Learn more...