CATH Classification
Level | CATH Code | Description |
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2 | Mainly Beta |
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2.40 | Beta Barrel |
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2.40.50 | OB fold (Dihydrolipoamide Acetyltransferase, E2P) |
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2.40.50.610 | Type II restriction enzyme SfiI, DNA-recognition domain |
Domain Context
CATH Clusters
Superfamily | Type II restriction enzyme SfiI, DNA-recognition domain |
Functional Family |
Enzyme Information
3.1.21.4 |
Type II site-specific deoxyribonuclease.
based on mapping to UniProt O52512
Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.
-!- Large group of enzymes which recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition site. -!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
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UniProtKB Entries (1)
O52512 |
T2S1_STRFI
Streptomyces fimbriatus
Type-2 restriction enzyme SfiI
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PDB Structure
PDB | 2EZV |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
A view of consecutive binding events from structures of tetrameric endonuclease SfiI bound to DNA
Embo J.
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