CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1280 | Alpha/beta knot |
|
3.40.1280.10 | SPOUT methyltransferase, trefoil knot domain |
Domain Context
CATH Clusters
| Superfamily | 3.40.1280.10 |
| Functional Family | Ribosomal RNA small subunit methyltransferase E |
Enzyme Information
| 2.1.1.193 |
16S rRNA (uracil(1498)-N(3))-methyltransferase.
based on mapping to UniProt O66552
S-adenosyl-L-methionine + uracil(1498) in 16S rRNA = S-adenosyl-L- homocysteine + N(3)-methyluracil(1498) in 16S rRNA.
-!- The enzyme specifically methylates uracil(1498) at N(3) in 16S rRNA.
|
UniProtKB Entries (1)
| O66552 |
RSME_AQUAE
Aquifex aeolicus VF5
Ribosomal RNA small subunit methyltransferase E
|
PDB Structure
| PDB | 2EGV |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of rRNA methyltransferase with SAM ligand
To be Published
|