CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.50 | OB fold (Dihydrolipoamide Acetyltransferase, E2P) |
|
2.40.50.40 |
Domain Context
CATH Clusters
| Superfamily | 2.40.50.40 |
| Functional Family | chromodomain-helicase-DNA-binding protein 3 isoform X1 |
Enzyme Information
| 3.6.4.12 |
DNA helicase.
based on mapping to UniProt Q14839
ATP + H(2)O = ADP + phosphate.
-!- DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA. -!- Some of them unwind duplex DNA with a 3' to 5' polarity (1,3,5,8), other show 5' to 3' polarity (10,11,12,13) or unwind DNA in both directions (14,15). -!- Some helicases unwind DNA as well as RNA (4,9). -!- May be identical with EC 3.6.4.13 (RNA helicase).
|
UniProtKB Entries (1)
| Q14839 |
CHD4_HUMAN
Homo sapiens
Chromodomain-helicase-DNA-binding protein 4
|
PDB Structure
| PDB | 2EE1 |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Solution structures of the Chromo domain of human chromodomain helicase-DNA-binding protein 4
To be Published
|