CATH Classification

Domain Context

CATH Clusters

Superfamily 2.70.98.10
Functional Family Glucan 1,4-alpha-glucosidase SusB

Enzyme Information

3.2.1.3
Glucan 1,4-alpha-glucosidase.
based on mapping to UniProt G8JZS4
Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D- glucose.
-!- Most forms of the enzyme can rapidly hydrolyze 1,6-alpha-D-glucosidic bonds when the next bond in the sequence is 1,4, and some preparations of this enzyme hydrolyze 1,6- and 1,3-alpha-D-glucosidic bonds in other polysaccharides. -!- This entry covers all such enzymes acting on polysaccharides more rapidly than on oligosaccharides. -!- EC 3.2.1.20 from mammalian intestine can catalyze similar reactions.

UniProtKB Entries (1)

G8JZS4
SUSB_BACTN
Bacteroides thetaiotaomicron VPI-5482
Glucan 1,4-alpha-glucosidase SusB

PDB Structure

PDB 2D73
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural and functional analysis of a glycoside hydrolase family 97 enzyme from Bacteroides thetaiotaomicron.
Kitamura, M., Okuyama, M., Tanzawa, F., Mori, H., Kitago, Y., Watanabe, N., Kimura, A., Tanaka, I., Yao, M.
J.Biol.Chem.