CATH Classification

Domain Context

CATH Clusters

Superfamily Metal-dependent hydrolases
Functional Family Ribonuclease P protein component 3

Enzyme Information

3.1.26.5
Ribonuclease P.
based on mapping to UniProt O59543
Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.
-!- Essential for tRNA processing; generates 5'-termini of mature tRNA molecules.

UniProtKB Entries (1)

O59150
RNP2_PYRHO
Pyrococcus horikoshii OT3
Ribonuclease P protein component 2

PDB Structure

PDB 2CZV
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of protein Ph1481p in complex with protein Ph1877p of archaeal RNase P from Pyrococcus horikoshii OT3: implication of dimer formation of the holoenzyme
Kawano, S., Nakashima, T., Kakuta, Y., Tanaka, I., Kimura, M.
J.Mol.Biol.
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