CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1350.10
Functional Family tRNA-splicing endonuclease

Enzyme Information

4.6.1.16
tRNA-intron lyase.
based on mapping to UniProt Q975R3
PretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.
-!- The enzyme catalyzes the final stage in the maturation of tRNA molecules. -!- Formerly EC 3.1.27.9.

UniProtKB Entries (1)

Q975R3
ENDA_SULTO
Sulfurisphaera tokodaii str. 7
TRNA-splicing endonuclease

PDB Structure

PDB 2CV8
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of tRNA-intron endonuclease from Sulfolobus tokodaii
Kato-Murayama, M., Bessho, Y., Shirouzu, M., Yokoyama, S.
To be Published