CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.100 | NADP-dependent oxidoreductase domain |
Domain Context
CATH Clusters
| Superfamily | NADP-dependent oxidoreductase domain |
| Functional Family | Aflatoxin B1 aldehyde reductase member 2 |
Enzyme Information
| 1.1.1.n11 |
Succinic semialdehyde reductase.
based on mapping to UniProt Q8CG76
4-hydroxybutanoate + NADP(+) = succinate semialdehyde + NADPH.
|
UniProtKB Entries (1)
| Q8CG76 |
ARK72_MOUSE
Mus musculus
Aflatoxin B1 aldehyde reductase member 2
|
PDB Structure
| PDB | 2C91 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structure of Mouse Succinic Semialdehyde Reductase Akr7A5: Structural Basis for Substrate Specificity.
Biochemistry
|