CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.1740 | Rna Polymerase Sigma Factor; Chain: A | |
1.10.1740.100 | Set2, Rpb1 interacting domain |
Domain Context
CATH Clusters
Superfamily | Set2, Rpb1 interacting domain |
Functional Family | Histone-lysine N-methyltransferase |
Enzyme Information
2.1.1.43 |
Histone-lysine N-methyltransferase.
based on mapping to UniProt P46995
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
|
UniProtKB Entries (1)
P46995 |
SET2_YEAST
Saccharomyces cerevisiae S288C
Histone-lysine N-methyltransferase, H3 lysine-36 specific
|
PDB Structure
PDB | 2C5Z |
External Links | |
Method | SOLUTION NMR |
Organism | |
Primary Citation |
Structure and carboxyl-terminal domain (CTD) binding of the Set2 SRI domain that couples histone H3 Lys36 methylation to transcription.
J. Biol. Chem.
|