CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.1170 | MutS, DNA mismatch repair protein, domain I | |
3.40.1170.60 |
Domain Context
CATH Clusters
Superfamily | 3.40.1170.60 |
Functional Family | DNA polymerase IV |
Enzyme Information
2.7.7.7 |
DNA-directed DNA polymerase.
based on mapping to UniProt Q97W02
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
|
UniProtKB Entries (1)
Q97W02 |
DPO4_SACS2
Saccharolobus solfataricus P2
DNA polymerase IV
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PDB Structure
PDB | 2C2D |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Efficient and High Fidelity Incorporation of Dctp Opposite 7,8-Dihydro-8-Oxodeoxyguanosine by Sulfolobus Solfataricus DNA Polymerase Dpo4
J.Biol.Chem.
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