CATH Classification

Domain Context

CATH Clusters

Superfamily NADP-dependent oxidoreductase domain
Functional Family Aflatoxin B1 aldehyde reductase member 2

Enzyme Information

1.1.1.n11
Succinic semialdehyde reductase.
based on mapping to UniProt O43488
4-hydroxybutanoate + NADP(+) = succinate semialdehyde + NADPH.

UniProtKB Entries (1)

O43488
ARK72_HUMAN
Homo sapiens
Aflatoxin B1 aldehyde reductase member 2

PDB Structure

PDB 2BP1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the Aflatoxin Aldehyde Reductase in Complex with Nadph
Debreczeni, J.E., Lukacik, P., Kavanagh, K., Dubinina, E., Bray, J., Colebrook, S., Haroniti, A., Edwards, A., Arrowsmith, C., Sundstrom, M., von Delft, F., Gileadi, O., Oppermann, U.
To be Published