CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 |
| Functional Family | 23S rRNA (Uracil(1939)-C(5))-methyltransferase RlmD |
Enzyme Information
| 2.1.1.190 |
23S rRNA (uracil(1939)-C(5))-methyltransferase.
based on mapping to UniProt P55135
S-adenosyl-L-methionine + uracil(1939) in 23S rRNA = S-adenosyl-L- homocysteine + 5-methyluracil(1939) in 23S rRNA.
-!- The enzyme specifically methylates uracil(1939) at C(5) in 23S rRNA. -!- The enzyme contains an [4Fe-4S] cluster coordinated by four conserved cysteine residues.
|
UniProtKB Entries (1)
| P55135 |
RLMD_ECOLI
Escherichia coli K-12
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD
|
PDB Structure
| PDB | 2BH2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A Unique RNA Fold in the Ruma-RNA-Cofactor Ternary Complex Contributes to Substrate Selectivity and Enzymatic Function
Cell(Cambridge,Mass.)
|