CATH Classification

Domain Context

CATH Clusters

Superfamily Yeast DNA topoisomerase - domain 1
Functional Family DNA topoisomerase I

Enzyme Information

UniProtKB Entries (2)

Q9GPZ9
Q9GPZ9_LEIIN
Leishmania infantum
DNA topoisomerase I
Q8WQM6
Q8WQM6_LEIDO
Leishmania donovani
DNA topoisomerase I-like protein

PDB Structure

PDB 2B9S
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The Structure of the Transition State of the Heterodimeric Topoisomerase I of Leishmania donovani as a Vanadate Complex with Nicked DNA.
Davies, D.R., Mushtaq, A., Interthal, H., Champoux, J.J., Hol, W.G.
J.Mol.Biol.
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