CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
Superfamily | Vaccinia Virus protein VP39 |
Functional Family | Release factor glutamine methyltransferase |
Enzyme Information
2.1.1.297 |
Peptide chain release factor N(5)-glutamine methyltransferase.
based on mapping to UniProt P0ACC1
S-adenosyl-L-methionine + [peptide chain release factor 1 or 2]-L- glutamine = S-adenosyl-L-homocysteine + [peptide chain release factor 1 or 2]-N(5)-methyl-L-glutamine.
-!- Modifies the glutamine residue in the universally conserved glycylglycylglutamine (GGQ) motif of peptide chain release factor, resulting in almost complete loss of release activity. -!- Formerly EC 2.1.1.n16.
|
UniProtKB Entries (1)
P0ACC1 |
PRMC_ECOLI
Escherichia coli K-12
Release factor glutamine methyltransferase
|
PDB Structure
PDB | 2B3T |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Molecular basis for bacterial class I release factor methylation by PrmC
Mol.Cell
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