CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family Histamine N-methyltransferase

Enzyme Information

2.1.1.8
Histamine N-methyltransferase.
based on mapping to UniProt P50135
S-adenosyl-L-methionine + histamine = S-adenosyl-L-homocysteine + N(tau)- methylhistamine.

UniProtKB Entries (1)

P50135
HNMT_HUMAN
Homo sapiens
Histamine N-methyltransferase

PDB Structure

PDB 2AOX
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for inhibition of histamine N-methyltransferase by diverse drugs
Horton, J.R., Sawada, K., Nishibori, M., Cheng, X.
J.Mol.Biol.
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