CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1400 |
Domain Context
CATH Clusters
| Superfamily | 3.40.50.1400 |
| Functional Family | Ferrochelatase |
Enzyme Information
| 4.99.1.1 |
Protoporphyrin ferrochelatase.
based on mapping to UniProt P32396
Protoheme + 2 H(+) = protoporphyrin + Fe(2+).
-!- The enzyme catalyzes the terminal step in the heme biosynthesis pathways of eukaryotes and Gram-negative bacteria.
|
UniProtKB Entries (1)
| P32396 |
HEMH_BACSU
Bacillus subtilis subsp. subtilis str. 168
Ferrochelatase
|
PDB Structure
| PDB | 2AC2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Metallation of the Transition-state Inhibitor N-methyl Mesoporphyrin by Ferrochelatase: Implications for the Catalytic Reaction Mechanism.
J.Mol.Biol.
|