CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.420 | Nucleotidyltransferase; domain 5 |
|
3.30.420.10 | Ribonuclease H-like superfamily/Ribonuclease H |
Domain Context
CATH Clusters
| Superfamily | Ribonuclease H-like superfamily/Ribonuclease H |
| Functional Family | Poly(A)-specific ribonuclease PARN |
Enzyme Information
| 3.1.13.4 |
Poly(A)-specific ribonuclease.
based on mapping to UniProt O95453
Exonucleolytic cleavage of poly(A) to 5'-AMP.
-!- Cleaves poly(A) in either the single- or double-stranded form.
|
UniProtKB Entries (1)
| O95453 |
PARN_HUMAN
Homo sapiens
Poly(A)-specific ribonuclease PARN
|
PDB Structure
| PDB | 2A1S |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural insight into poly(A) binding and catalytic mechanism of human PARN
Embo J.
|