CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.150 | DNA polymerase; domain 1 |
|
1.10.150.190 | Translation initiation factor 2; subunit 1; domain 2 |
Domain Context
CATH Clusters
| Superfamily | Translation initiation factor 2; subunit 1; domain 2 |
| Functional Family | Translation initiation factor 2, alpha subunit |
Enzyme Information
UniProtKB Entries (2)
| P19525 |
E2AK2_HUMAN
Homo sapiens
Interferon-induced, double-stranded RNA-activated protein kinase
|
| P20459 |
IF2A_YEAST
Saccharomyces cerevisiae S288C
Eukaryotic translation initiation factor 2 subunit alpha
|
PDB Structure
| PDB | 2A1A |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Higher-Order Substrate Recognition of eIF2alpha by the RNA-Dependent Protein Kinase PKR.
Cell(Cambridge,Mass.)
|