CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.50 | OB fold (Dihydrolipoamide Acetyltransferase, E2P) |
|
2.40.50.140 | Nucleic acid-binding proteins |
Domain Context
CATH Clusters
| Superfamily | Nucleic acid-binding proteins |
| Functional Family | Eukaryotic translation initiation factor 2 subunit alpha |
Enzyme Information
UniProtKB Entries (2)
| P19525 |
E2AK2_HUMAN
Homo sapiens
Interferon-induced, double-stranded RNA-activated protein kinase
|
| P20459 |
IF2A_YEAST
Saccharomyces cerevisiae S288C
Eukaryotic translation initiation factor 2 subunit alpha
|
PDB Structure
| PDB | 2A19 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Higher-Order Substrate Recognition of eIF2alpha by the RNA-Dependent Protein Kinase PKR.
Cell(Cambridge,Mass.)
|
