CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family Casein kinase II subunit alpha

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P28523
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P28523
CSK2A_MAIZE
Zea mays
Casein kinase II subunit alpha

PDB Structure

PDB 1ZOE
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Inspecting the structure-activity relationship of protein kinase CK2 inhibitors derived from tetrabromo-benzimidazole.
Battistutta, R., Mazzorana, M., Sarno, S., Kazimierczuk, Z., Zanotti, G., Pinna, L.A.
Chem.Biol.
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