CATH Classification
Level | CATH Code | Description |
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3 | Alpha Beta |
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3.40 | 3-Layer(aba) Sandwich |
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3.40.50 | Rossmann fold |
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3.40.50.10740 | Class I glutamine amidotransferase-like |
Domain Context
CATH Clusters
Superfamily | Class I glutamine amidotransferase-like |
Functional Family |
Enzyme Information
3.4.17.13 |
Muramoyltetrapeptide carboxypeptidase.
based on mapping to UniProt Q9HTZ1
GlcNAc-MurNAc-L-alanyl-gamma-D-glutamyl-meso-diaminopimelyl-D-alanine + H(2)O = GlcNAc-MurNAc-L-alanyl-gamma-D-glutamyl-meso-diaminopimelate + D-alanine.
-!- Variants are known from various microorganisms. -!- Involved in peptidoglycan synthesis, catalyzing both decarboxylation and transpeptidation. -!- Stimulated by divalent cations such as magnesium and calcium, but not zinc. -!- Inhibited by thiol-blocking reagents, but unaffected by penicillin.
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UniProtKB Entries (1)
Q9HTZ1 |
LDC_PSEAE
Pseudomonas aeruginosa PAO1
Murein tetrapeptide carboxypeptidase
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PDB Structure
PDB | 1ZL0 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
X-ray crystal structure of hypothetical protein PA5198 at 1.1 A resolution.
To be Published
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