CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family tRNA (guanine-N(7)-)-methyltransferase

Enzyme Information

2.1.1.33
tRNA (guanine(46)-N(7))-methyltransferase.
based on mapping to UniProt P67506
S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.
-!- The enzyme specifically methylates guanine(46) at N(7) in tRNA.

UniProtKB Entries (1)

P67506
TRMB_STRPN
Streptococcus pneumoniae TIGR4
TRNA (guanine-N(7)-)-methyltransferase

PDB Structure

PDB 1YZH
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structure of the Conserved Methyltransferase from Streptococcus pneumoniae TIGR4
Kim, Y., Li, H., Collart, F., Joachimiak, A.
To be Published