CATH Classification

Domain Context

CATH Clusters

Superfamily Aromatic compound dioxygenase
Functional Family Protocatechuate 3,4-dioxygenase alpha chain

Enzyme Information

1.13.11.3
Protocatechuate 3,4-dioxygenase.
based on mapping to UniProt P00436
3,4-dihydroxybenzoate + O(2) = 3-carboxy-cis,cis-muconate.
-!- The enzyme, which participates in the degradation of aromatic compounds, catalyzes the intradiol addition of both oxygen atoms from molecular oxygen, resulting in ortho-cleavage of the aromatic ring. -!- The type of cleavage leads to mineralization via the intermediate 3-oxoadipate. -!- Formerly EC 1.13.1.3 and EC 1.99.2.3.

UniProtKB Entries (1)

P00437
PCXB_PSEPU
Pseudomonas putida
Protocatechuate 3,4-dioxygenase beta chain

PDB Structure

PDB 1YKL
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Roles of the equatorial tyrosyl iron ligand of protocatechuate 3,4-dioxygenase in catalysis
Valley, M.P., Brown, C.K., Burk, D.L., Vetting, M.W., Ohlendorf, D.H., Lipscomb, J.D.
Biochemistry
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