CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
Functional Family Ribonuclease Z

Enzyme Information

3.1.26.11
Ribonuclease Z.
based on mapping to UniProt P54548
Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.
-!- No cofactor requirements.

UniProtKB Entries (1)

P54548
RNZ_BACSU
Bacillus subtilis subsp. subtilis str. 168
Ribonuclease Z

PDB Structure

PDB 1Y44
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for substrate binding, cleavage and allostery in the tRNA maturase RNase Z.
de la Sierra-Gallay, I.L., Pellegrini, O., Condon, C.
Nature