CATH Classification

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family Tyrosine--tRNA ligase

Enzyme Information

6.1.1.1
Tyrosine--tRNA ligase.
based on mapping to UniProt P12063
ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + L-tyrosyl-tRNA(Tyr).

UniProtKB Entries (1)

P12063
SYYM_NEUCR
Neurospora crassa OR74A
Tyrosine--tRNA ligase, mitochondrial

PDB Structure

PDB 1Y42
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
A tyrosyl-tRNA synthetase adapted to function in group I intron splicing by acquiring a new RNA binding surface.
Paukstelis, P.J., Coon, R., Madabusi, L., Nowakowski, J., Monzingo, A., Robertus, J., Lambowitz, A.M.
Mol.Cell