CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.390 | Collagenase (Catalytic Domain) |
|
3.40.390.10 | Collagenase (Catalytic Domain) |
Domain Context
CATH Clusters
| Superfamily | Collagenase (Catalytic Domain) |
| Functional Family | Calmodulin-sensitive adenylate cyclase |
Enzyme Information
| 4.6.1.1 |
Adenylate cyclase.
based on mapping to UniProt P40136
ATP = 3',5'-cyclic AMP + diphosphate.
-!- Also acts on dATP to form 3',5'-cyclic dAMP. -!- Requires pyruvate. -!- Activated by NAD(+) in presence of EC 2.4.2.31.
|
UniProtKB Entries (2)
| P40136 |
CYAA_BACAN
Bacillus anthracis
Calmodulin-sensitive adenylate cyclase
|
| P0DP25 |
CALM3_HUMAN
Homo sapiens
Calmodulin-3
|
PDB Structure
| PDB | 1XFU |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.
EMBO J.
|
