CATH Domain 1wao102

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.60	4-Layer Sandwich
	3.60.21	Purple Acid Phosphatase; chain A, domain 2
	3.60.21.10	Metallo-dependent phosphatases

Domain Context

CATH Clusters

Superfamily	3.60.21.10
Functional Family	Serine/threonine-protein phosphatase

Enzyme Information

3.1.3.16

Protein-serine/threonine phosphatase.

based on mapping to UniProt P53041

[a protein]-serine/threonine phosphate + H(2)O = [a protein]- serine/threonine + phosphate.

-!- A group of enzymes removing the serine- or threonine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase (cf. EC 3.1.3.48). -!- The spleen enzyme also acts on phenolic phosphates and phosphamides (cf. EC 3.9.1.1).

UniProtKB Entries (1)

P53041

PPP5_HUMAN

Homo sapiens

Serine/threonine-protein phosphatase 5

PDB Structure

PDB	1WAO
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Molecular Basis for Tpr Domain-Mediated Regulation of Protein Phosphatase 5 Yang, J., Roe, S.M., Cliff, M.J., Williams, M.A., Ladbury, J.E., Cohen, P.T., Barford, D. Embo J.