CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.1360 | Gyrase A; domain 2 |
|
3.30.1360.120 | Probable tRNA modification gtpase trme; domain 1 |
Domain Context
CATH Clusters
| Superfamily | Probable tRNA modification gtpase trme; domain 1 |
| Functional Family | Aminomethyltransferase |
Enzyme Information
| 2.1.2.10 |
Aminomethyltransferase.
based on mapping to UniProt P27248
[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH(3).
-!- A component, with EC 1.4.4.2 and EC 1.8.1.4, of the glycine cleavage system, formerly known as glycine synthase. -!- The glycine cleavage system is composed of four components that only loosely associate: the P protein (EC 1.4.4.2), the T protein (EC 2.1.2.10), the L protein (EC 1.8.1.4) and the lipoyl-bearing H protein.
|
UniProtKB Entries (1)
| P27248 |
GCST_ECOLI
Escherichia coli K-12
Aminomethyltransferase
|
PDB Structure
| PDB | 1VLO |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of aminomethyltransferase (T protein; tetrahydrofolate-dependent) of glycine cleavage system (np417381) from Escherichia coli k12 at 1.70 A resolution
To be published
|
