CATH Classification

Domain Context

CATH Clusters

Superfamily PurM-like, N-terminal domain
Functional Family

Enzyme Information

6.3.5.3
Phosphoribosylformylglycinamidine synthase.
based on mapping to UniProt Q9X0X3
ATP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H(2)O = ADP + phosphate + 2-(formamido)-N(1)-(5-phospho-D- ribosyl)acetamidine + L-glutamate.

UniProtKB Entries (1)

Q9X0X3
PURL_THEMA
Thermotoga maritima MSB8
Phosphoribosylformylglycinamidine synthase subunit PurL

PDB Structure

PDB 1VK3
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of phosphoribosylformylglycinamidine synthase II (smPurL) from Thermotoga maritima at 2.15 A resolution.
Mathews, I.I., Krishna, S.S., Schwarzenbacher, R., McMullan, D., Abdubek, P., Ambing, E., Canaves, J.M., Chiu, H.J., Deacon, A.M., DiDonato, M., Elsliger, M.A., Godzik, A., Grittini, C., Grzechnik, S.K., Hale, J., Hampton, E., Han, G.W., Haugen, J., Jaroszewski, L., Klock, H.E., Koesema, E., Kreusch, A., Kuhn, P., Lesley, S.A., Levin, I., Miller, M.D., Moy, K., Nigoghossian, E., Paulsen, J., Quijano, K., Reyes, R., Spraggon, G., Stevens, R.C., van den Bedem, H., Velasquez, J., White, A., Wolf, G., Xu, Q., Hodgson, K.O., Wooley, J., Wilson, I.A.
Proteins
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