CATH Domain 1vk3A01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.650	Phosphoribosyl-aminoimidazole Synthetase; Chain A, domain 2
	3.90.650.10	PurM-like C-terminal domain

Domain Context

CATH Clusters

Superfamily	PurM-like C-terminal domain
Functional Family

Enzyme Information

6.3.5.3

Phosphoribosylformylglycinamidine synthase.

based on mapping to UniProt Q9X0X3

ATP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H(2)O = ADP + phosphate + 2-(formamido)-N(1)-(5-phospho-D- ribosyl)acetamidine + L-glutamate.

UniProtKB Entries (1)

Q9X0X3

PURL_THEMA

Thermotoga maritima MSB8

Phosphoribosylformylglycinamidine synthase subunit PurL

PDB Structure

PDB	1VK3
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal structure of phosphoribosylformylglycinamidine synthase II (smPurL) from Thermotoga maritima at 2.15 A resolution. Mathews, I.I., Krishna, S.S., Schwarzenbacher, R., McMullan, D., Abdubek, P., Ambing, E., Canaves, J.M., Chiu, H.J., Deacon, A.M., DiDonato, M., Elsliger, M.A., Godzik, A., Grittini, C., Grzechnik, S.K., Hale, J., Hampton, E., Han, G.W., Haugen, J., Jaroszewski, L., Klock, H.E., Koesema, E., Kreusch, A., Kuhn, P., Lesley, S.A., Levin, I., Miller, M.D., Moy, K., Nigoghossian, E., Paulsen, J., Quijano, K., Reyes, R., Spraggon, G., Stevens, R.C., van den Bedem, H., Velasquez, J., White, A., Wolf, G., Xu, Q., Hodgson, K.O., Wooley, J., Wilson, I.A. Proteins