CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.10860 | Leucine Dehydrogenase, chain A, domain 1 |
Domain Context
CATH Clusters
Superfamily | Leucine Dehydrogenase, chain A, domain 1 |
Functional Family | Quinate/shikimate dehydrogenase |
Enzyme Information
1.1.1.282 |
Quinate/shikimate dehydrogenase.
based on mapping to UniProt P0A6D5
(1) L-quinate + NAD(P)(+) = 3-dehydroquinate + NAD(P)H. (2) Shikimate + NAD(P)(+) = 3-dehydroshikimate + NAD(P)H.
-!- The enzyme is found in bacteria (mostly, but not exclusively, Gram- positive bacteria), fungi, and plants. -!- It participates in the degradation of quinate and shikimate with a strong preference for NAD+ as a cofactor. -!- While the enzyme can act on both quinate and shikimate, activity is higher with the former.
|
UniProtKB Entries (1)
P0A6D5 |
YDIB_ECOLI
Escherichia coli K-12
Quinate/shikimate dehydrogenase
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PDB Structure
PDB | 1VI2 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Structural analysis of a set of proteins resulting from a bacterial genomics project
Proteins
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