CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.720 | Alkaline Phosphatase, subunit A |
|
3.40.720.10 | Alkaline Phosphatase, subunit A |
Domain Context
CATH Clusters
| Superfamily | Alkaline Phosphatase, subunit A |
| Functional Family | Alkaline phosphatase |
Enzyme Information
| 3.1.3.1 |
Alkaline phosphatase.
based on mapping to UniProt P00634
A phosphate monoester + H(2)O = an alcohol + phosphate.
-!- Active at a high pH optimum. -!- Wide specificity. -!- Also catalyzes transphosphorylations. -!- Some enzymes hydrolyze diphosphate (cf. EC 3.6.1.1).
|
UniProtKB Entries (1)
| P00634 |
PPB_ECOLI
Escherichia coli K-12
Alkaline phosphatase
|
PDB Structure
| PDB | 1URA |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Kinetic and structural consequences of replacing the aspartate bridge by asparagine in the catalytic metal triad of Escherichia coli alkaline phosphatase.
J.Mol.Biol.
|