CATH Classification
Domain Context
CATH Clusters
| Superfamily | Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 |
| Functional Family |
Enzyme Information
| 1.14.12.18 |
Biphenyl 2,3-dioxygenase.
based on mapping to UniProt Q53122
Biphenyl + NADH + O(2) = (1S,2R)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD(+).
-!- The enzyme from Burkholderia fungorum strain LB400 (previously Pseudomonas sp.) is part of a multicomponent system composed of an NADH:ferredoxin oxidoreductase (FAD cofactor), a [2Fe-2S] Rieske-type ferredoxin, and a terminal oxygenase that contains a [2Fe-2S] Rieske- type iron-sulfur cluster and a catalytic mononuclear nonheme iron center. -!- Chlorine-substituted biphenyls can also act as substrates. -!- Similar to the three-component enzyme systems EC 1.14.12.3 and EC 1.14.12.11.
|
UniProtKB Entries (1)
| Q53123 |
BPHA2_RHOJR
Rhodococcus jostii RHA1
Biphenyl 2,3-dioxygenase subunit beta
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PDB Structure
| PDB | 1ULJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Rhodococcus |
| Primary Citation |
Crystal Structure of the Terminal Oxygenase Component of Biphenyl Dioxygenase Derived from Rhodococcus sp. Strain RHA1
J.Mol.Biol.
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