CATH Domain 1u3oA01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.30	SH3 type barrels.
	2.30.30.40	SH3 Domains

Domain Context

CATH Clusters

Superfamily	SH3 Domains
Functional Family	kalirin isoform X1

Enzyme Information

2.7.11.1

Non-specific serine/threonine protein kinase.

based on mapping to UniProt P97924

ATP + a protein = ADP + a phosphoprotein.

-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P97924

KALRN_RAT

Rattus norvegicus

Kalirin

PDB Structure

PDB	1U3O
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism	Escherichia
Primary Citation	Regulation of RhoGEF Activity by Intramolecular and Intermolecular SH3 Domain Interactions. Schiller, M.R., Chakrabarti, K., King, G.F., Schiller, N.I., Eipper, B.A., Maciejewski, M.W. J.Biol.Chem.