CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.1150 | Aspartate Aminotransferase, domain 1 |
|
3.90.1150.10 | Aspartate Aminotransferase, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Aspartate Aminotransferase, domain 1 |
| Functional Family | 4-aminobutyrate aminotransferase |
Enzyme Information
| 2.6.1.48 |
5-aminovalerate transaminase.
based on mapping to UniProt P22256
5-aminopentanoate + 2-oxoglutarate = 5-oxopentanoate + L-glutamate.
|
| 2.6.1.19 |
4-aminobutyrate--2-oxoglutarate transaminase.
based on mapping to UniProt P22256
4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate.
-!- Some preparations also act on beta-alanine, 5-aminopentanoate and (R,S)-3-amino-2-methylpropanoate.
|
UniProtKB Entries (1)
| P22256 |
GABT_ECOLI
Escherichia coli K-12
4-aminobutyrate aminotransferase GabT
|
PDB Structure
| PDB | 1SZU |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Kinetic and Crystallographic Analysis of Active Site Mutants of Escherichia coligamma-Aminobutyrate Aminotransferase.
Biochemistry
|
