CATH Classification

Domain Context

CATH Clusters

Superfamily DNA gyrase/topoisomerase IV, subunit A, C-terminal
Functional Family

Enzyme Information

5.6.2.3
DNA topoisomerase (ATP-hydrolyzing).
based on mapping to UniProt O51396
ATP-dependent breakage, passage and rejoining of double-stranded DNA.
-!- The enzyme can introduce negative superhelical turns into double- stranded circular DNA. -!- One unit has nicking-closing activity, and another catalyzes super- twisting and hydrolysis of ATP (cf. EC 5.6.2.2). -!- Formerly EC 5.99.1.3.

UniProtKB Entries (1)

O51396
GYRA_BORBU
Borreliella burgdorferi B31
DNA gyrase subunit A

PDB Structure

PDB 1SUU
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The C-terminal domain of DNA gyrase A adopts a DNA-bending beta-pinwheel fold.
Corbett, K.D., Shultzaberger, R.K., Berger, J.M.
Proc.Natl.Acad.Sci.Usa
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