CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.25 | Alpha Horseshoe |
|
1.25.20 | 70-kda Soluble Lytic Transglycosylase; domain 1 |
|
1.25.20.10 | Bacterial muramidases |
Domain Context
CATH Clusters
| Superfamily | Bacterial muramidases |
| Functional Family | Soluble lytic murein transglycosylase |
Enzyme Information
| 4.2.2.n1 |
Peptidoglycan lytic exotransglycosylase.
based on mapping to UniProt P0AGC3
Exolytic cleavage of the (1->4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in peptidoglycan, from either the reducing or the non-reducing ends of the peptidoglycan chains, with concomitant formation of a 1,6-anhydrobond in the MurNAc residue.
|
UniProtKB Entries (1)
| P0AGC3 |
SLT_ECOLI
Escherichia coli K-12
Soluble lytic murein transglycosylase
|
PDB Structure
| PDB | 1SLY |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of the 70-kDa soluble lytic transglycosylase complexed with bulgecin A. Implications for the enzymatic mechanism.
Biochemistry
|
