CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.167 | Regulator of G-protein Signalling 4; domain 2 |
|
1.10.167.10 | Regulator of G-protein Signalling 4, domain 2 |
Domain Context
CATH Clusters
| Superfamily | Regulator of G-protein Signalling 4, domain 2 |
| Functional Family | Rho guanine nucleotide exchange factor 1 |
Enzyme Information
UniProtKB Entries (3)
| P10824 |
GNAI1_RAT
Rattus norvegicus
Guanine nucleotide-binding protein G(i) subunit alpha-1
|
| P27601 |
GNA13_MOUSE
Mus musculus
Guanine nucleotide-binding protein subunit alpha-13
|
| Q92888 |
ARHG1_HUMAN
Homo sapiens
Rho guanine nucleotide exchange factor 1
|
PDB Structure
| PDB | 1SHZ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure of the p115RhoGEF rgRGS domain-Galpha13/i1 chimera complex suggests convergent evolution of a GTPase activator.
Nat.Struct.Mol.Biol.
|