CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 |
| Functional Family |
Enzyme Information
| 2.1.1.297 |
Peptide chain release factor N(5)-glutamine methyltransferase.
based on mapping to UniProt Q9WYV8
S-adenosyl-L-methionine + [peptide chain release factor 1 or 2]-L- glutamine = S-adenosyl-L-homocysteine + [peptide chain release factor 1 or 2]-N(5)-methyl-L-glutamine.
-!- Modifies the glutamine residue in the universally conserved glycylglycylglutamine (GGQ) motif of peptide chain release factor, resulting in almost complete loss of release activity. -!- Formerly EC 2.1.1.n16.
|
UniProtKB Entries (1)
| Q9WYV8 |
PRMC_THEMA
Thermotoga maritima MSB8
Release factor glutamine methyltransferase
|
PDB Structure
| PDB | 1SG9 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
A novel mode of dimerization via formation of a glutamate anhydride crosslink in a protein crystal structure.
Proteins
|
