CATH Domain 1s5rB00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.1160	Paired amphipathic helix 2 (pah2 repeat)
	1.20.1160.11	Paired amphipathic helix

Domain Context

CATH Clusters

Superfamily	Paired amphipathic helix
Functional Family	Paired amphipathic helix protein Sin3a

Enzyme Information

UniProtKB Entries (1)

SIN3A_MOUSE

Mus musculus

Paired amphipathic helix protein Sin3a

PDB Structure

PDB	1S5R
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism	Escherichia
Primary Citation	HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations. Swanson, K.A., Knoepfler, P.S., Huang, K., Kang, R.S., Cowley, S.M., Laherty, C.D., Eisenman, R.N., Radhakrishnan, I. Nat.Struct.Mol.Biol.