CATH Classification

Domain Context

CATH Clusters

Superfamily Single helix bin
Functional Family rho-associated protein kinase 2

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q13464
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P61586
RHOA_HUMAN
Homo sapiens
Transforming protein RhoA

PDB Structure

PDB 1S1C
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural Insights into the Interaction of ROCKI with the Switch Regions of RhoA.
Dvorsky, R., Blumenstein, L., Vetter, I.R., Ahmadian, M.R.
J.Biol.Chem.