CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.420 | Ricin (A subunit); domain 1 | |
3.40.420.10 | Ricin (A subunit), domain 1 |
Domain Context
CATH Clusters
Superfamily | Ricin (A subunit), domain 1 |
Functional Family |
Enzyme Information
3.2.2.22 |
rRNA N-glycosylase.
based on mapping to UniProt Q9FBI2
Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
-!- Ricin A-chain and related toxins show this activity. -!- Naked rRNA is attacked more slowly than rRNA in intact ribosomes. -!- Naked rRNA from Escherichia coli is cleaved at a corresponding position.
|
UniProtKB Entries (1)
Q7BQ98 |
STXB_SHIDY
Shigella dysenteriae
Shiga toxin subunit B
|
PDB Structure
PDB | 1R4Q |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Structure of Shiga Toxin Type 2 (Stx2) from Escherichia coli O157:H7.
J.Biol.Chem.
|